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Product Name: Huperzine A
Synonyms: (+/-)-SELAGINE;[+/-]-SELAGINE;SELAGINE;(+/-)-HUPERAZINE A;HUPERAZINE A;
(+/-)-HUPERZINE A;HUPERZINE A;(+/-)-Selagine
Product Categories: Natural Plant Extract;Acetylcholine receptor;Herb extract
Mol File: 120786-18-7.mol
Huperzine A is a naturally occurring sesquiterpene alkaloid compound found in the firmoss Huperzia serrata and in varying quantities in other Huperzia species, including H. elmeri, H. carinat, and H. aqualupian. It is known as an acetylcholinesterase inhibitor, which means that it stops an enzyme from breaking down acetylcholine which results in increases in acetylcholine.
Huperzine A has been investigated as a possible treatment for diseases characterized by neurodegeneration, particularly Alzheimer's disease. Huperzine A is also marketed as a dietary supplement with claims made for its ability to improve memory and mental function. Huperzine A has also been postulated as a potential treatment for myasthenia gravis.
Huperzine A is a cognitive enhancer that inhibits an enzyme that degrades the learning neurotransmitter, acetylcholine; due to this, a relative increase occurs. It belongs to the cholinergics class of molecules, and may be useful in fighting cognitive decline in the elderly. May need to be cycled.
While Huperzine A will have an effect on its own, stacking it with the right components may yield even better results.
Taking Huperzine A in combination with a choline source such as Alpha GPC can increase the amount of acetylcholine in the brain further, enhancing the effect of huperzine A.
A racetam is also a good choice for stacking with huperzine A. Racetams are thought to activate glutamate receptors that are located near acetylcholine receptors. This activity sensitizes the acetylcholine receptors so they are more likely to become activated. Sensitizing the receptors with a racetam and increasing the amount of acetylcholine with huperzine A enhances the nootropic effect of both drugs.
Huperzine A is also often paired with Noopept, a powerful and popular nootropic.
For improving memory in young people, Huperzine A can be taken at 100 mg twice a day. It has been used at 50 to 200 mcg twice a day to treat Alzheimer's disease. We suggest that regular users take a break from the drug every few weeks to avoid physical habituation. For example, after taking huperzine A daily for three weeks, consider cycling off of it for one week before resuming regular use.
Huperzine A does not need to be taken with food. It is quickly absorbed into the body and will begin to enhance memory immediately. It has a very long half-life in the body, and a single dose will provide benefits for over 24 hours. The drug has been shown to be quite capable of passing the blood-brain barrier after oral ingestion and quickly accumulates in the cerebrospinal fluid.