• Nootropics Pharmaceutical Powder Prl-8-53 HCl For Promoting Intelligence CAS:51352-87-5

Nootropics Pharmaceutical Powder Prl-8-53 HCl For Promoting Intelligence CAS:51352-87-5

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Nootropics Pharmaceutical Powder Prl-8-53 HCl For Promoting Intelligence CAS:51352-87-5

Quick Details:


Chemical name:Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate

Synonyms:PRL-8053;PRL-8-53;Methyl 3-(2-(benzyl(Methyl)aMino)ethyl)benzoate hydrochloride;3-(2-Benzyl(methyl)aminoethyl)benzoic acid methyl ester hydrochloride;m-[2-(Benzylmethylamino)ethyl]benzoic acid methyl ester hydrochloride;Benzoic acid, 3-(2-(Methyl(phenylMethyl)aMino)ethyl)-, Methyl ester, hydrochloride

CAS 51352-87-5


MW 319.82578

Dosage: Subjects in human trials have been given up to 100 mg a day and did not appear to develop any negative side effects

PRL-8-53 HCL Descriptions:

PRL-8-53 (chemical name Methyl 3-(2-(benzyl(methyl)amino)ethyl)benzoate) is a synthetic nootropic compound discovered in 1972 and patented in 1975 by the late Dr. Nikolaus Hansl, a neuropharmacologist at Creighton University in Omaha, Nebraska. Preliminary animal tests indicated that the compound was both safe and significantly nootropic, boosting avoidance learning in rodents with no adverse effects.

But the real interest in PRL-8-53 was sparked by a 1978 study on human volunteers, which showed that a single dose of the compound could improve word retention scores by more than 200%.

PRL-8-53 HCL Applications:

PRL-8-53's exact mechanisms of action are not well understood, but it is generally believed to regulate the brain's production of and response to several crucial neurotransmitters. In his reports on human and animal studies Hansl indicated that PRL-8-53 potentiates dopamine, partially restricts production of serotonin, and enhances the brain's response to acetylcholine.

Though Hansl's research report on the 1978 human study suggests those actions, it does not clearly delineate the mechanism of action.The fact that older subjects saw the most nootropic benefit from taking the drug supports the concept that dopamine modulation plays a major role in PLR-8-53's effects. Up-regulating the normal age-related lessening of dopamine production that is associated with cognitive decline could have a significant positive impact on both learning and memory.

Product namePRL-8-53 HCL
CAS No.51352-87-5Outer Packing1KG
Production date4 th , May. 2018Shelf life2 years
Standard adoptedIn-house standard
Items of analysisSpecificationResults
AppearanceOff white solid powderConform
IdentificationConform with NMRConforms
Melting Point149-152ºC150-151ºC
Loss on Drying≤0.50%0.23%
Residue on ignition≤1.0%0.28%
Heavy metalsNMT 20PPMConforms
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