• Raw Material Nootropic Powders Nsi-189 CAS1270138-40-3 For Anti Depression

Raw Material Nootropic Powders Nsi-189 CAS1270138-40-3 For Anti Depression

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Raw Material Nootropic Powders Nsi-189 CAS1270138-40-3 For Anti Depression

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Pharmaceutical Raw Material Nootropics Powders Nsi-189 For Anti-Depression CAS:1270138-40-3


Product Description:


Nootropics Powder CAS 1270138-40-3 Nsi-189 /Nsi 189

Quick details :

99% Raw Nootropics Antidepressant Powder NSI - 189 CAS: 1270138-40-3

Product Name: NSI-189

Other Name: [2-[(3-Methylbutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]

CAS : 15180-02-6

Purity: 99% min.

Molecular Formula: C22H30N4O

Molecular Weight: 366.50

Purity :NSI-189 has a purity not less than 99%.


NSI-189 Describtion :


NSI-189 is a benzylphiperizine-aminiopyridine, nootropic and neurogenic research chemical created by Neuralstem, Inc. that was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro . In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression . The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.


The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimer's disease, and major depressive disorder (MDD).


NSI-189's Method of Action:


Although it has been demonstrated in rats and chimps, the suggestion that having too small of a hippocampus causes depression and other diseases in humans is still technically just a theory. NSI-189 increases hippocampal volume in adult mice by 20%, a region of the brain that is one of the first to suffer damage resulting in memory loss, disorientation, encephalitis, and hypoxia from disease's such as Alzheimer's .




1. As pharmaceutical raw materials for clearing heat, anti-inflammation, detumescence and so on, it is mainly used in pharmaceutical field;


2. As the raw material of product for benefiting stomach, increasing energy and boosting the


immunity, widely used in health industry.


Nsi-189 Effect:


1) Enhance cognition and memory formation.

2) Anxiolytic properties.

3) Anti-depressive effect .

4) Treatment of Alzheimer's and Parkinson's disease.

5) Increase coordination.

6) Improves mood.

7) Help fight fatigue.

8) Prevent oxidation within the brain.

9) Treat alcohol related brain damage.

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