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Product Name: Galantamine Hydrobromide
CAS No.: 1953-04-4
Product Categories: Alkaloids;Alkaloids (Others);Biochemistry;Functional Products;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Acetylcholine receptor;API;Chiral Reagents;Reminyl;Other APIs;Pharmaceutical intermediates
MP 256 °C
Storage temp. −20°C
Chemical Properties: White to Off-White Powder
Usage: A selective acetylcholinesterase inhibitor. A therapeutic agent for the treatment and prevention of Alzheimer's disease and other diseases resulting from reduced neuronal metabolism; Alzheimer treatment;Cholinesterase inhibitor;anticholinesterase, analgesic, antiAlzheimer
Galantamine hydrobromide is the hydrobromide salt of galantamine and is a cholinesterase inhibitor can be extracted from Amaryllidaceae Lycoris plant. The III-phase clinical trials in the United Kingdom in 1998 have showed that this drug had dual mechanism of action of both inhibiting acetylcholinesterase and regulating nicotinic receptors.
Therefore, galantamine can improve the cognitive abilities of Alzheimer's patients and has been already applied as the drug of the treatment of mild to severe Alzheimer's disease (AD) drugs and has entered into market in EC countries. "Chinese Pharmacopoeia" has included the both the raw material and injection of galantamine hydrobromide.
It can be used for the treatment of neurological diseases and trauma-induced movement disorders, multiple neuritis, and radiculitis.