GTS21 GTS-21 cas: 156223-05-1
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Product name : GTS-21 (DMXB-A) DMBX-anabaseine;
Cas No.: 156223-05-1
Chemical name : GTS-21 dihydrochloride; HY-14564A; DMXB-A
Synonyms : 3-(2,4-dimethoxy-benzylidene)anabaseine
Standard purity : >99%
Appearance :Yellow powder
GTS-21 (DMBX-A) is a derivative of the natural product anabaseine that acts as a partial agonist at neural nicotinic acetylcholine receptors. It binds to both the α4β2 and α7 subtypes, but activates only the α7 to any significant extent.
Both GTS-21 itself and its demethylated active metabolite 4-OH-GTS-21 display nootropic and neuroprotective effects, and GTS-21 is being investigated for the treatment of Alzheimer's disease,nicotine dependence,and, most significantly, for schizophrenia.