• Antidepressan Raw Powder Nsi-189 Phosphate CAS 1270138-41-4 Pharmaceutical Intermediate

Antidepressan Raw Powder Nsi-189 Phosphate CAS 1270138-41-4 Pharmaceutical Intermediate

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Pharmaceutical Intermediate Raw Powder Nsi-189 Phosphate for Antidepressant CAS:1270138-41-4

Quick details :

99% Raw Nootropics Antidepressant Powder NSI - 189 CAS: 1270138-40-3

Product Name: NSI-189

Other Name: [2-[(3-Methylbutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]

CAS : 15180-02-6

Purity: 99% min.

Molecular Formula: C22H30N4O

Molecular Weight: 366.50

Purity :NSI-189 has a purity not less than 99%

NSI-189 Describtion :

NSI-189 is a benzylphiperizine-aminiopyridine, nootropic and neurogenic research chemical created by Neuralstem, Inc. that was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro . In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression . The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.

The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimer's disease, and major depressive disorder (MDD).

Product nameNSI-189
CAS No.1270138-40-3Outer Packing 
Production dateDec. 15. 2016.Shelf lifeDec. 14th. 2019
Standard adoptedin-house standard
>Items of analysisSpecificationResults
AppearanceOff-white powderConfrom
IdentificationIR and HPLC spectrum shall conform to the standard sampleconform
Melting Point83ºC~86ºC84.3ºC~85.6ºC
Loss on DryingLess than 0.5%0.29%
Purity(On Dried Base,HPLC)NLT 99.5 %99.62%
Total ImpurityLess than 0.5%0.33%
Residue On Ignition≤0.2%0.16%
Heavy metal≤20ppmconform

NSI-189's Method of Action:

Although it has been demonstrated in rats and chimps, the suggestion that having too small of a hippocampus causes depression and other diseases in humans is still technically just a theory. NSI-189 increases hippocampal volume in adult mice by 20%, a region of the brain that is one of the first to suffer damage resulting in memory loss, disorientation, encephalitis, and hypoxia from disease's such as Alzheimer's .

Nsi-189 Effect:

1) Enhance cognition and memory formation.

2) Anxiolytic properties.

3) Anti-depressive effect .

4) Treatment of Alzheimer's and Parkinson's disease.

5) Increase coordination.

6) Improves mood.

7) Help fight fatigue.

8) Prevent oxidation within the brain.

9) Treat alcohol related brain damage.

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