Antidepressan Raw Powder Nsi-189 Phosphate CAS 1270138-41-4 Pharmaceutical Intermediate
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Pharmaceutical Intermediate Raw Powder Nsi-189 Phosphate for Antidepressant CAS:1270138-41-4
Quick details :
99% Raw Nootropics Antidepressant Powder NSI - 189 CAS: 1270138-40-3
Product Name: NSI-189
Other Name: [2-[(3-Methylbutyl)amino]-3-pyridinyl][4-(phenylmethyl)-1-piperazinyl]
CAS : 15180-02-6
Purity: 99% min.
Molecular Formula: C22H30N4O
Molecular Weight: 366.50
Purity :NSI-189 has a purity not less than 99%
NSI-189 Describtion :
NSI-189 is a benzylphiperizine-aminiopyridine, nootropic and neurogenic research chemical created by Neuralstem, Inc. that was derived from pyrazine and nicotinamide. Studies have shown that it stimulates neurogenesis of human hippocampus-derived neural stem cells in vivo and vitro . In healthy adult mice, NSI-189 has been shown to increase the hippocampal volume by 20% and reverse behavioral symptoms in mouse depression models, meaning at the source it could address depression . The hippocampus is responsible for spatial navigation, along with the consolidation of information from short-term memory to long-term memory.
The chemical entity stimulates new neuron growth in the hippocampus, which is an area of the brain that is believed to be contributory in conditions such as post-traumatic stress disorder (PTSD), Alzheimer's disease, and major depressive disorder (MDD).
|CAS No.||1270138-40-3||Outer Packing|
|Production date||Dec. 15. 2016.||Shelf life||Dec. 14th. 2019|
|Standard adopted||in-house standard|
|>Items of analysis||Specification||Results|
|Identification||IR and HPLC spectrum shall conform to the standard sample||conform|
|Loss on Drying||Less than 0.5%||0.29%|
|Purity(On Dried Base,HPLC)||NLT 99.5 %||99.62%|
|Total Impurity||Less than 0.5%||0.33%|
|Residue On Ignition||≤0.2%||0.16%|
NSI-189's Method of Action:
Although it has been demonstrated in rats and chimps, the suggestion that having too small of a hippocampus causes depression and other diseases in humans is still technically just a theory. NSI-189 increases hippocampal volume in adult mice by 20%, a region of the brain that is one of the first to suffer damage resulting in memory loss, disorientation, encephalitis, and hypoxia from disease's such as Alzheimer's .
1) Enhance cognition and memory formation.
2) Anxiolytic properties.
3) Anti-depressive effect .
4) Treatment of Alzheimer's and Parkinson's disease.
5) Increase coordination.
6) Improves mood.
7) Help fight fatigue.
8) Prevent oxidation within the brain.
9) Treat alcohol related brain damage.